She moved to Spain with her father and her brother, Ariel Rot, in 1976 and started acting. Her first major role was in Iván Zulueta's Arrebato (1979). After appearing in Pedro Almodóvar's debut feature _Pepi, Luci, Bom y otras chicas del montón (1980)_ she kept working with him in Laberinto de pasiones (1982), Entre tinieblas (1983) and ¿Qué he hecho YO para merecer esto!! (1984). In 1995 she moved back to Argentina and became a national movie, stage and TV star. Besides appearing in the U.S. co-produced thriller The Stranger (1987), she mostly starred in Argentine films including Un lugar en el mundo (1992), hit detective drama Cenizas del paraíso (1997) and family drama Martín (Hache) (1997), which gained her a Goya Award. She teamed up with Almodóvar again starring in Todo sobre mi madre (1999).